Use of diffusion tensor imaging in glioma resection

• Published in: Neurosurgical focus Vol. 34; no. 4; p. E1
• Main Authors: Abdullah, Kalil G, Lubelski, Daniel, Nucifora, Paolo G P, Brem, Steven
• Format: Journal Article
• Language: English
• Published: United States 01.04.2013
• Subjects: Brain Neoplasms - diagnosis; Brain Neoplasms - metabolism; Brain Neoplasms - surgery; Diffusion Tensor Imaging - methods; Diffusion Tensor Imaging - utilization; Glioma - diagnosis; Glioma - metabolism; Glioma - surgery; Humans; Monitoring, Intraoperative - methods; Neurosurgical Procedures - methods
• ISSN: 1092-0684; 1092-0684
• DOI: 10.3171/2013.1.FOCUS12412

Diffusion tensor imaging (DTI) is increasingly used in the resection of both high- and low-grade gliomas. Whereas conventional MRI techniques provide only anatomical information, DTI offers data on CNS connectivity by enabling visualization of important white matter tracts in the brain. Importantly, DTI allows neurosurgeons to better guide their surgical approach and resection. Here, the authors review basic scientific principles of DTI, include a primer on the technology and image acquisition, and outline the modality's evolution as a frequently used tool for glioma resection. Current literature supporting its use is summarized, highlighting important clinical studies on the application of DTI in preoperative planning for glioma resection, preoperative diagnosis, and postoperative outcomes. The authors conclude with a review of future directions for this technology.