Highly Cis-Selective Horner-Wadsworth-Emmons (HWE) Reaction of Methyl Bis(2,4-Difluorophenyl) Phosphonoacetate

Of the previously reported Horner-Wadsworth-Emmons (HWE) reaction, the olefination of methyl bis(2,4-difluorophenyl)phosphonoacetate (la) with various aldehydes gave unsaturated esters in the highest cis-selectivity.

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Bibliographic Details
Published inSynthetic communications Vol. 27; no. 14; pp. 2387 - 2392
Main Authors Kokin, Keisuke, Motoyoshiya, Jiro, Hayashi, Sadao, Aoyama, Hiromu
Format Journal Article
LanguageEnglish
Published NEW YORK Taylor & Francis Group 01.07.1997
Marcel Dekker Inc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
Z-UNSATURATED ESTERS
OLEFINATION
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Summary:Of the previously reported Horner-Wadsworth-Emmons (HWE) reaction, the olefination of methyl bis(2,4-difluorophenyl)phosphonoacetate (la) with various aldehydes gave unsaturated esters in the highest cis-selectivity.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397919708004100