Biochemical effects of Amanita muscaria extract in mice

The biochemical effects of mushroom extracts were studied in order to classify poisonous mushrooms in terms of their biochemical effects; this would provide useful information for clinical treatment. The species of mushrooms studied were Amanita muscaria, Amanita pantherina and Amanita rubrovolvata,...

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Published inFood Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) Vol. 24; no. 5; pp. 459 - 464_1
Main Authors Yamaura, Y, Komiyama, S. (Nagano-ken. Research Inst. for Health and Pollution (Japan)), Fukuhara, M, Takabatake, E, Hashimoto, T
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society for Food Hygiene and Safety 1983
Subjects
Amanita muscaria
biochemical effect
blood glucose
CHAMPIGNON TOXIQUE
CHOLINESTERASE
COLINESTERASA
EXTRACTOS
EXTRACTS
EXTRAIT
GLICOGENO
GLUCOSA
GLUCOSE
GLYCOGEN
GLYCOGENE
HONGOS VENENOSOS
liver glycogen
POISONOUS FUNGI
poisonous mushroom
serum cholinesterase
TOXICIDAD
TOXICITE
TOXICITY
UREA
urea nitrogen
UREE
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Abstract The biochemical effects of mushroom extracts were studied in order to classify poisonous mushrooms in terms of their biochemical effects; this would provide useful information for clinical treatment. The species of mushrooms studied were Amanita muscaria, Amanita pantherina and Amanita rubrovolvata, which are known to cause nervous system disorder in man. After intraperitoneal injection of aqueous extract of A. muscaria into male mice, biochemical changes in the serum and liver were noted within 3 hours, but the values returned to normal within 6 hours after the injection. The activity of serum cholinesterase was decreased moderately at 30 minutes after the injection. The liver glycogen was decreased at 1 hour after the injection. The blood glucose level was increased at 1 hour and decreased at 3 hours after the injection. The blood urea nitrogen was decreased significantly, but serum transaminase activities were unaffected. Among the poisonous mushrooms examined, A. rubrovolvata was the most potent.
AbstractList The biochemical effects of mushroom extracts were studied in order to classify poisonous mushrooms in terms of their biochemical effects; this would provide useful information for clinical treatment. The species of mushrooms studied were Amanita muscaria, Amanita pantherina and Amanita rubrovolvata, which are known to cause nervous system disorder in man. After intraperitoneal injection of aqueous extract of A. muscaria into male mice, biochemical changes in the serum and liver were noted within 3 hours, but the values returned to normal within 6 hours after the injection. The activity of serum cholinesterase was decreased moderately at 30 minutes after the injection. The liver glycogen was decreased at 1 hour after the injection. The blood glucose level was increased at 1 hour and decreased at 3 hours after the injection. The blood urea nitrogen was decreased significantly, but serum transaminase activities were unaffected. Among the poisonous mushrooms examined, A. rubrovolvata was the most potent.
Author Yamaura, Y
Takabatake, E
Komiyama, S. (Nagano-ken. Research Inst. for Health and Pollution (Japan))
Hashimoto, T
Fukuhara, M
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References 11) Glock, G. E., McLean, P.: Biochem. J. 55, 400-408 (1953).
4) 山浦由郎, 前沢久, 高畠英伍, 橋本隆: 食衛誌. 22, 203-208 (1981).
24) Ammon, R.: Pflug. Arch, ges. Physiol. 233, 486-491 (1934).
7) Miller, G. L.: Anal. Chem. 31, 964 (1961).
10) Swanson, M. A.: J. Biol. Chem. 184, 647-659 (1955).
17) Müller, G. F. R., Eugster, C. H.: Helv. Chim. Acta. 48, 910-926 (1965).
19) Wieland, Th., Motzel, W., Merz, H.: Liebigs Ann. Chem. 581, 10-16 (1953).
6) Moris, D. L.: Science 107, 254-255 (1948).
20) Styne, T.: Mitt. Gebiete. Lehensm. Hyg. 70, 246-253 (1976).
26) Kuenzle, C. C., Waser, P. G.: Heiv. Physiol. Acta. 16, 44-57 (1958).
21) 横山和正: 遺伝. 34, 58-59 (1980).
14) 竹本常松: 遺伝. 23, 22-25 (1969).
5) 山浦由郎, 前沢久, 高畠英伍, 橋本隆: 食衛誌. 23, 314-318 (1982).
27) 宮木高明:“薬物と生体”現代生物科学 14. p. 213, 岩波書店 (1976).
13) 竹本常松, 中島正, 佐久間礼子: 薬誌. 84, 1233-1234 (1964).
23) Keeser, E.: Klin. Wschr. 17, 1811 (1938).
9) Ellman, G. L.: Arch. Biochem. Biophys. 82, 70-77 (1959).
25) Fraser, P. J.: Brit. J. Pharmacol. 12, 47-52 (1957).
12) 小林義雄: 日菌報. 21, 141-146 (1980).
22) 山崎幹夫: 医学のあゆみ 112, No. 13, 912-913 (1979).
18) Eugster, C. H.: Helv. Chim. Acta. 39, 1002-1023 (1956).
28) Benedict, R. G.: “Mushroom toxins other than Amanita, in Kadis, S., Ciegler, A. and Ajl, S. J. (ed.)-Microbial Toxins-” 8, p. 293-298 (1972) Academic Press, New York.
2) 長沢武, 河原勲:“長野県山菜・キノコ図鑑”p. 274-279 (1979) 信濃毎日新聞社.
3) 長野県衛生部食品衛生課編: 食品衛生課関係事業成績 (昭和46～56年).
16) 山村秀夫:“中毒ハンドブック”p. 546 (1979) 広川書店.
8) Radin, N. S.: “Methods in Enzymology” 14, p. 245-254 (1969) Academic Press, New York.
1) 厚生省環境衛生局食品衛生課編: 全国食中毒事件録 (昭和39～56年).
15) 田坂定孝:“臨床中毒学”p. 306-310 (1960) 金原出版.
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StartPage 459
SubjectTerms Amanita muscaria
biochemical effect
blood glucose
CHAMPIGNON TOXIQUE
CHOLINESTERASE
COLINESTERASA
EXTRACTOS
EXTRACTS
EXTRAIT
GLICOGENO
GLUCOSA
GLUCOSE
GLYCOGEN
GLYCOGENE
HONGOS VENENOSOS
liver glycogen
POISONOUS FUNGI
poisonous mushroom
serum cholinesterase
TOXICIDAD
TOXICITE
TOXICITY
UREA
urea nitrogen
UREE
Title Biochemical effects of Amanita muscaria extract in mice
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