Photoactivated leucocyte-rich platelet-rich plasma treatment in reduction of bone marrow edema in hip osteoarthritis

• Published in: Regenerative medicine Vol. 17; no. 8; pp. 521 - 531
• Main Authors: de Castro, Jeimylo C, Henares-Esguerra, Elvira L, Olivia S Tamayo-Shih, Maria Bida, Wang, Daniel, Chang Chien, George C
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.08.2022
• Subjects: bone marrow edema; bone marrow lesion; cytokines; growth factors; hip pain; LR-PRP; platelet-rich plasma; subchondral edema; growth factors; hip pain; bone marrow lesion; cytokines; bone marrow edema; platelet-rich plasma; LR-PRP; subchondral edema
• ISSN: 1746-0751; 1746-076X
• DOI: 10.2217/rme-2021-0165

To describe the successful treatment of bone marrow edema in the setting of hip osteoarthritis using ultrasound-guided injection of photoactivated leukocyte-rich platelet-rich plasma (LR-PRP). Outpatient clinic. 65-year old female with antalgic and listing gait. The patient presented with a 2-week history of left hip pain. Exam revealed restriction and pain at end range of motion. Imaging showed extensive bone marrow edema and hip effusion. The patient underwent four weekly photoactivated LR-PRP treatments. The patient reported a significant reduction in pain with MRI showing an extensive resolution of bone marrow edema and complete pain relief at 2 and 6 months post-treatment, respectively. Photoactivated LR-PRP may be considered as a treatment option for patients with marrow edema in the setting of hip osteoarthritis. To describe the successful treatment of bone marrow swelling in the setting of hip osteoarthritis using ultrasound-guided injection of enhanced platelet-rich plasma (PRP). Outpatient clinic. 65-year old female with an abnormal gait. The patient presented with a 2-week history of left hip pain. Exam revealed restriction and pain at end range of motion. Imaging showed extensive bone marrow and hip swelling. The patient underwent four weekly enhanced PRP treatments. The patient reported a significant reduction in pain with MRI showing an extensive resolution of bone marrow edema and complete pain relief at 2 and 6 months post-treatment, respectively. This specific enhanced PRP may be considered as a treatment option for patients with marrow edema in the setting of hip osteoarthritis.