Lipase catalyzed enantioselective transesterification of 5-acyloxy-2(5H)-furanones
Several lipases catalyse the transesterification of γ-acyloxyfuranones in organic solvents with high enantioselectivities. This method has been used for the kinetic resolution of 5-acetoxy-2(5H)-furanone, 5-acetoxy-4-methyl-2(5H)-furanone and 5-propionyloxy-2(5H)-furanone, in e.e.'s ranging fro...
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Published in | Tetrahedron letters Vol. 35; no. 45; pp. 8441 - 8444 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
OXFORD
Elsevier Ltd
07.11.1994
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Several lipases catalyse the transesterification of γ-acyloxyfuranones in organic solvents with high enantioselectivities. This method has been used for the kinetic resolution of 5-acetoxy-2(5H)-furanone, 5-acetoxy-4-methyl-2(5H)-furanone and 5-propionyloxy-2(5H)-furanone, in e.e.'s ranging from 68–98%.
Several lipases in organic solvents catalyse the enantioselective transesterification of 5-acyloxy-2(5H)-furanones with e.e.'s ranging from 68–98%. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/S0040-4039(00)74428-5 |