Symptom Relief Is Possible in Elderly Dying COVID-19 Patients: A National Register Study

Increasing numbers of people dying from COVID-19 are reported, but data are lacking on the way they die. To study symptoms and symptom relief during the last week of life, comparing nursing homes with hospitals. The Swedish Register of Palliative Care with national coverage was used. Breakthrough sy...

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Bibliographic Details
Published inJournal of palliative medicine Vol. 24; no. 4; p. 514
Main Authors Strang, Peter, Bergström, Jonas, Lundström, Staffan
Format Journal Article
LanguageEnglish
Published United States 01.04.2021
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Summary:Increasing numbers of people dying from COVID-19 are reported, but data are lacking on the way they die. To study symptoms and symptom relief during the last week of life, comparing nursing homes with hospitals. The Swedish Register of Palliative Care with national coverage was used. Breakthrough symptoms were registered as Yes/No. Symptom relief was recorded on a 3-grade scale as . All deaths in COVID-19 were contrasted to deaths in a reference population (deaths 2019). Deaths at nursing homes were compared with deaths in hospitals. All deaths in hospitals or nursing homes (  = 490) were analyzed. Deaths in other settings (specialized palliative care wards [  = 11], in palliative home care [  = 2], or in their own homes [  = 8]) were excluded (  = 21). Only patients with expected deaths (  = 390) were entered in the final analysis. Breathlessness as a breakthrough symptom was more common in COVID-19 patients than in the 2019 reference population (  < 0.001) and relief of breathlessness, as well as anxiety, delirium, and death rattles was less successful in COVID-19 patients (  < 0.05 to  < 0.01 in different comparisons). Patients were older in nursing homes than in hospitals (86.6 years vs. 80.9 years,  < 0.001) and more often female (48% vs. 34%,  < 0.001). Breakthrough of breathlessness was much more frequently reported in hospital settings than in nursing homes, 73% versus 35% (  < 0.0001), and complete relief was more rarely possible in hospitals, 20% versus 42% (  < 0.01). The proportion of partial relief+complete relief was comparable, 92% versus 95% (ns). Also, anxiety and pain were more often completely relieved in nursing homes (  < 0.01 in both comparisons). The lower symptom prevalence in nursing homes may be explained by elderly frail residents dying already in the first phase of the COVID-19 disease, before acute respiratory distress syndrome develops.
ISSN:1557-7740
DOI:10.1089/jpm.2020.0249