Synthesis of 2-Arylidene-3-Oxo-Derivatives of Glycyrrhetic Acid

Claisen–Schmidt reactions of 3-oxoglycyrrhetic acid with aromatic aldehydes in EtOH–NaOH (4N) synthesized 2-arylidene-3-oxo-derivatives in 65–70% yields. The structures of the compounds were confirmed by PMR and 13 C NMR spectra using 2D correlation methods.

Saved in:
Bibliographic Details
Published inChemistry of natural compounds Vol. 58; no. 4; pp. 669 - 673
Main Authors Baltina, L. A., Nugumanov, T. R., Karimova, E. R.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.07.2022
Springer Nature
Springer
Springer Nature B.V
Subjects
Aldehydes
Chemistry
Chemistry and Materials Science
Chemistry, Medicinal
Chemistry, Organic
Chemistry/Food Science
Claisen-Schmidt reaction
Life Sciences & Biomedicine
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacology & Pharmacy
Physical Sciences
Plant metabolites
Plant Sciences
Science & Technology
synthesis
glycyrrhetic acid
2-arylidene-3-oxo-derivatives
triterpenoids
DERIVATIVES
Online AccessGet full text

Cover

More Information
Summary:Claisen–Schmidt reactions of 3-oxoglycyrrhetic acid with aromatic aldehydes in EtOH–NaOH (4N) synthesized 2-arylidene-3-oxo-derivatives in 65–70% yields. The structures of the compounds were confirmed by PMR and 13 C NMR spectra using 2D correlation methods.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03766-y