Sendai virus NP gene codes for a 524 amino acid NP protein

The complete nucleoprotein (NP) gene sequences of the Sendai virus Fushimi and 6/94 strains were determined. For both viruses an open reading frame of 524 amino acids can be predicted for the NP proteins. By comparing the sequences with others reported in the literature, the 5' noncoding region...

Full description

Saved in:
Bibliographic Details
Published inVirus genes Vol. 5; no. 1; p. 25
Main Authors Neubert, W J, Eckerskorn, C, Homann, H E
Format Journal Article
LanguageEnglish
Published United States 01.01.1991
Subjects
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Codon - genetics
Genes, Viral
Molecular Sequence Data
Nucleoproteins - genetics
Open Reading Frames
Parainfluenza Virus 1, Human - genetics
Peptide Fragments - isolation & purification
Protein Conformation
RNA, Messenger - genetics
Sequence Homology, Nucleic Acid
Transcription, Genetic
Trypsin
Online AccessGet more information

Cover

More Information
Summary:The complete nucleoprotein (NP) gene sequences of the Sendai virus Fushimi and 6/94 strains were determined. For both viruses an open reading frame of 524 amino acids can be predicted for the NP proteins. By comparing the sequences with others reported in the literature, the 5' noncoding region and the middle third of the coding region were found to be highly conserved. The carboxyl terminal part carries nine amino acid changes and a completely different sequence of the carboxyl terminus with a seven amino acid extension. This carboxyl terminus of the Sendai virus NP protein was confirmed using tryptic peptide sequence analysis.
ISSN:0920-8569
DOI:10.1007/BF00571728