Vaccination dilemma in the thermodynamic limit

• Published in: Chaos (Woodbury, N.Y.) Vol. 33; no. 2; p. 023132
• Main Authors: Benjamin, Colin, U M, Arjun Krishnan
• Format: Journal Article
• Language: English
• Published: United States 01.02.2023
• Subjects: Adult; Aged; COVID-19; COVID-19 Vaccines; Humans; Non-alcoholic Fatty Liver Disease; Pandemics; Thermodynamics; Vaccination; Young Adult
• ISSN: 1089-7682
• DOI: 10.1063/5.0137393

The vaccination game is a social dilemma that refers to the conundrum individuals face (to get immunized or not) when the population is exposed to an infectious disease. The model has recently gained much traction due to the COVID-19 pandemic since the public perception of vaccines plays a significant role in disease dynamics. This paper studies the vaccination game in the thermodynamic limit with an analytical method derived from the 1D Ising model called Nash equilibrium mapping. The individual dilemma regarding vaccination comes from an internal conflict wherein one tries to balance the perceived advantages of immunizing with the apparent risks associated with vaccination, which they hear through different news media. We compare the results of Nash equilibrium (NE) mapping from other 1D Ising-based models, namely, Darwinian evolution (DE) and agent-based simulation. This study aims to analyze the behavior of an infinite population regarding what fraction of people choose to vaccinate or not vaccinate. While Nash equilibrium mapping and agent-based simulation agree mostly, DE strays far from the two models. DE fails to predict the equilibrium behavior of players in the population reasonably. We apply the results of our study to analyze the AstraZeneca (AZ) COVID-19 vaccine risk vs disease deaths debate, both via NE mapping and the agent-based method. Both predict nearly 100% AZ vaccine coverage for people aged above 40, notwithstanding the risk. At the same time, younger people show a slight reluctance. We predict that while government intervention via vaccination mandates and/or advertisement campaigns are unnecessary for the older population, for the younger population (ages: 20-39), some encouragement from the government via media campaigns and/or vaccine mandates may be necessary.