A New Flavonoid Glycoside from Schizonepeta annua

A new flavonoid glycoside 1 was isolated from Schizonepeta annua (Pall.) Schischk. by column chromatography. Its structure was determined to be acacetin 7-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→6)]-β-D-glucopyranoside (1) by spectroscopic data ( 1 H NMR, 13 C NMR, 1 H− 1 H COSY, HSQC, and...

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Published inChemistry of natural compounds Vol. 55; no. 3; pp. 458 - 460
Main Authors Shen, Jie, Chen, Jia, Li, Ji-Ping, Shao, Jian-Hua
Format Journal Article
LanguageEnglish
Published New York Springer US 01.05.2019
Springer Nature
Springer
Springer Nature B.V
Subjects
Chemistry
Chemistry, Medicinal
Chemistry, Organic
Chromatography
Column chromatography
Columnar structure
Flavone glycosides
Flavonoids
Glucosidase
Isoflavones
Life Sciences & Biomedicine
Medicine
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacology & Pharmacy
Pharmacy
Physical Sciences
Plant Sciences
Science & Technology
Steppes
Technology
Type 2 diabetes
flavonoid glycoside
glucosidase inhibitory activity
Schizonepeta annua
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Summary:A new flavonoid glycoside 1 was isolated from Schizonepeta annua (Pall.) Schischk. by column chromatography. Its structure was determined to be acacetin 7-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→6)]-β-D-glucopyranoside (1) by spectroscopic data ( 1 H NMR, 13 C NMR, 1 H− 1 H COSY, HSQC, and HMBC) and chemical methods. In addition, the α-glucosidase inhibitory activity of compound 1 was evaluated.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-019-02713-8