6′-Sialyllactose Alleviates Muscle Fatigue through Reduced Blood Lactate Level after Treadmill Exercise in Mice

• Published in: Nutrients Vol. 16; no. 17; p. 2957
• Main Authors: Park, Eun-Jung, Kim, Li-La, Lee, Jie-Oh, Lee, Hay-Young, Kim, Yong-An, Go, Hiroe
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.09.2024
• Subjects: Animals; Biomarkers; blood glucose; Blood Glucose - drug effects; Blood Glucose - metabolism; blood serum; brain; breast milk; Cytochrome; digestive system; E coli; Endurance; Enzymes; Exercise; Fitness equipment; Food; food intake; Glucose; Kinases; Laboratories; lactic acid; Lactic Acid - blood; Lactose - analogs & derivatives; Lactose - pharmacology; lipids; Male; males; Metabolism; Mice; Mice, Inbred C57BL; Mitochondria; Muscle fatigue; Muscle Fatigue - drug effects; muscle fibers; Muscle, Skeletal - drug effects; Muscle, Skeletal - metabolism; muscles; oxidative phosphorylation; Physical Conditioning, Animal; Physiology; Production increases; protein synthesis; Proteins; Software; United States > US; South Korea; Japan; oxidative phosphorylation protein complexes; anti-fatigue; muscle fiber type; lactate; 6′-sialyllactose

6′-Sialyllactose (6′-SL), found in human breast milk, exhibits anti-inflammatory, immune function-enhancing, brain development-promoting, and gut health-improving effects. However, its effects on muscle fatigue remain unknown. Here, we aimed to investigate the effects of 6′-SL on blood lactate level...