Polymer gel dosimetry for experimental verification of conformal small animal irradiation at a preclinical research platform

Abstract In translational research, there is a need for preclinical studies of high quality that corresponds to the conformal dose distributions conventionally delivered to humans in the modern radiotherapy clinic. To facilitate this need, novel preclinical systems consist of preclinical radiation p...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 2630; no. 1; pp. 12034 - 12037
Main Authors Konradsson, E, Blomstedt, M, Gustafsson, C Jamtheim, Bäck, S Å J, Ceberg, C, Ceberg, S
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.11.2023
Subjects
Clinical Medicine
Dosimeters
Feasibility studies
Klinisk medicin
Medical and Health Sciences
Medicin och hälsovetenskap
Physics
Polymer gels
Polymers
Radiation therapy
Radiologi och bildbehandling
Radiology, Nuclear Medicine and Medical Imaging
Spatial resolution
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Summary:Abstract In translational research, there is a need for preclinical studies of high quality that corresponds to the conformal dose distributions conventionally delivered to humans in the modern radiotherapy clinic. To facilitate this need, novel preclinical systems consist of preclinical radiation platforms and small animal treatment planning systems. However, small-field dosimetry is challenging and requires dosimeters with high spatial resolution. In this study we demonstrate the feasibility of experimentally validating the dose distribution in small fields at a preclinical X-ray research platform using a polymer gel dosimeter and MRI-readout.
ISSN:1742-6588
1742-6596
1742-6596
DOI:10.1088/1742-6596/2630/1/012034