Antifungal activity of propolis extract against Candida albicans in patients with vulvovaginal candidiasis [version 1; peer review: awaiting peer review]
Background: The aim was to evaluate the antifungal activity of propolis extract against Candida albicans (or C. albicans) in patients with vulvovaginal candidiasis. Methods: The research presents a quantitative approach with an experimental design, with a population of C. albicans strains isolated f...
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| Published in | F1000 research Vol. 11; p. 1185 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
2022
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| Abstract | Background: The aim was to evaluate the antifungal activity of propolis extract against
Candida albicans (or
C. albicans) in patients with vulvovaginal candidiasis.
Methods: The research presents a quantitative approach with an experimental design, with a population of
C. albicans strains isolated from patients diagnosed with vulvovaginal candidiasis who were admitted to the Gynecology Service of the Maria del Socorro Clinic, district of Ate, Lima; a sample of 34 strains was chosen in total, considering three repetitions per strain, obtaining 102 experimental units.
The antifungal susceptibility test was carried out by the disc diffusion plate method using a single concentration of propolis extract, with fluconazole as a positive control.
Results: Propolis extract was shown to inhibit all strains of
C. albicans, as was fluconazole, with the effect of the latter being significantly greater than that of the product under investigation.
Conclusions: The conclusion is that propolis extract does show antifungal activity against
C. albicans in patients with vulvovaginal candidiasis. |
|---|---|
| AbstractList | Background:
The aim was to evaluate the antifungal activity of propolis extract against
Candida albicans
(or
C. albicans
) in patients with vulvovaginal candidiasis.
Methods:
The research presents a quantitative approach with an experimental design, with a population of
C. albicans
strains isolated from patients diagnosed with vulvovaginal candidiasis who were admitted to the Gynecology Service of the Maria del Socorro Clinic, district of Ate, Lima; a sample of 34 strains was chosen in total, considering three repetitions per strain, obtaining 102 experimental units.
The antifungal susceptibility test was carried out by the disc diffusion plate method using a single concentration of propolis extract, with fluconazole as a positive control.
Results:
Propolis extract was shown to inhibit all strains of
C. albicans
, as was fluconazole, with the effect of the latter being significantly greater than that of the product under investigation.
Conclusions:
The conclusion is that propolis extract does show antifungal activity against
C. albicans
in patients with vulvovaginal candidiasis. Background: The aim was to evaluate the antifungal activity of propolis extract against Candida albicans (or C. albicans) in patients with vulvovaginal candidiasis. Methods: The research presents a quantitative approach with an experimental design, with a population of C. albicans strains isolated from patients diagnosed with vulvovaginal candidiasis who were admitted to the Gynecology Service of the Maria del Socorro Clinic, district of Ate, Lima; a sample of 34 strains was chosen in total, considering three repetitions per strain, obtaining 102 experimental units. The antifungal susceptibility test was carried out by the disc diffusion plate method using a single concentration of propolis extract, with fluconazole as a positive control. Results: Propolis extract was shown to inhibit all strains of C. albicans, as was fluconazole, with the effect of the latter being significantly greater than that of the product under investigation. Conclusions: The conclusion is that propolis extract does show antifungal activity against C. albicans in patients with vulvovaginal candidiasis. |
| Author | Esteves Pairazaman, Ambrocio Teodoro Collanque Meza, Vadir Ali Jesús Collanque Pinto, Jesus Daniel Malpartida Quispe, Federico Martin Alvarado Chávez, Britt Horna Sandoval, Consuelo Berta Ibarra Fretell, Walter Gregorio Leon Apac, Gabriel Rodríguez Loyola, Gina Andrea |
| Author_xml | – sequence: 1 givenname: Ambrocio Teodoro orcidid: 0000-0003-4168-0850 surname: Esteves Pairazaman fullname: Esteves Pairazaman, Ambrocio Teodoro email: ambrocio.esteves@uwiener.edu.pe organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 2 givenname: Jesus Daniel surname: Collanque Pinto fullname: Collanque Pinto, Jesus Daniel organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 3 givenname: Britt surname: Alvarado Chávez fullname: Alvarado Chávez, Britt organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 4 givenname: Gabriel surname: Leon Apac fullname: Leon Apac, Gabriel organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 5 givenname: Consuelo Berta surname: Horna Sandoval fullname: Horna Sandoval, Consuelo Berta organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 6 givenname: Federico Martin surname: Malpartida Quispe fullname: Malpartida Quispe, Federico Martin organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru – sequence: 7 givenname: Vadir Ali Jesús surname: Collanque Meza fullname: Collanque Meza, Vadir Ali Jesús organization: Instituto SISE, Lima, 15046, Peru – sequence: 8 givenname: Walter Gregorio orcidid: 0000-0003-4276-5389 surname: Ibarra Fretell fullname: Ibarra Fretell, Walter Gregorio organization: Universidad Cesar Vallejo, Lima, Peru – sequence: 9 givenname: Gina Andrea surname: Rodríguez Loyola fullname: Rodríguez Loyola, Gina Andrea organization: Universidad Privada Norbert Wiener, Lima, 15072, Peru |
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| Copyright | Copyright: © 2022 Esteves Pairazaman AT et al. |
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| Keywords | Vulvovaginal candidiasis Antifungal activity Propolis extract Candida Albicans |
| Language | English |
| License | http://creativecommons.org/licenses/by/4.0/: This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| Snippet | Background: The aim was to evaluate the antifungal activity of propolis extract against
Candida albicans (or
C. albicans) in patients with vulvovaginal... Background: The aim was to evaluate the antifungal activity of propolis extract against Candida albicans (or C. albicans ) in patients with vulvovaginal... |
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