Case 27-2009: A Woman with Fever, Rash, and Lymphadenopathy

To the Editor: In Case 27-2009 (Aug. 27 issue), 1 the patient's clearly stated initial symptom, a week-long systemic reaction that began 4 hours after a fire-ant sting and resolved in response to prednisone, was not discussed in the context of the final diagnosis, angioimmunoblastic T-cell lymp...

Full description

Saved in:
Bibliographic Details
Published inThe New England journal of medicine Vol. 361; no. 23; pp. 2294 - 2295
Main Author Sotos, John G
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 03.12.2009
Subjects
Ant Venoms - immunology
Autoimmune diseases
Diagnosis, Differential
Female
Hospitals
Humans
Hypersensitivity, Delayed - etiology
Lymphoma, Large-Cell, Immunoblastic - immunology
Thyroid diseases
Online AccessGet full text

Cover

More Information
Summary:To the Editor: In Case 27-2009 (Aug. 27 issue), 1 the patient's clearly stated initial symptom, a week-long systemic reaction that began 4 hours after a fire-ant sting and resolved in response to prednisone, was not discussed in the context of the final diagnosis, angioimmunoblastic T-cell lymphoma. The patient's reaction is similar to the marked delayed-hypersensitivity reactions long known to occur after mosquito bites in persons with chronic lymphocytic leukemia. 2 Such reactions may be the presenting symptom of this condition. Other states of immune dysregulation, 3 including lymphomas, 4 , 5 have also been linked to such reactions. Although mosquitoes and fire ants are . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc0910183