Volatile nitrosamines in the main stream smoke of black tobacco

The cigarettes studied are smoked through an automatic device. The mainstream smoke is trapped in Citrate-Phosphate buffer pH 4.5 containing 20 mM ascorbic acid. The volatile nitrosamines are extracted in dichloromethane, purified on alumina column, then analysed by gas-chromatography with a thermal...

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Bibliographic Details
Published inJournal of cancer research and clinical oncology Vol. 108; no. 1; p. 157
Main Authors Truhaut, R, Phu Lich, N, Castegnaro, M, Bourgade, M C, Martin, C
Format Journal Article
LanguageEnglish
Published Germany 01.01.1984
Subjects
Nicotiana - analysis
Nitrosamines - analysis
Plants, Toxic
Smoke - analysis
Volatilization
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Summary:The cigarettes studied are smoked through an automatic device. The mainstream smoke is trapped in Citrate-Phosphate buffer pH 4.5 containing 20 mM ascorbic acid. The volatile nitrosamines are extracted in dichloromethane, purified on alumina column, then analysed by gas-chromatography with a thermal energy analyzer (TEA) detector. The two main volatile nitrosamines quantified are: Nitrosodimethylamine and Nitrosopyrrolidine.
ISSN:0171-5216
1432-1335
DOI:10.1007/BF00390989