High prevalence of vitamin D deficiency and insufficiency in patients with manifest Huntington disease An explorative study

Vitamin D deficiency and insufficiency are common in older institutionalized people and known to be associated with muscle weakness, impaired balance and increased fall risk. Falls and balance problems are common in people with Huntington disease (HD). Despite this, the prevalence of vitamin D defic...

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Published inDermato-endocrinology Vol. 5; no. 3; pp. 348 - 351
Main Authors Chel, Victor GM, Ooms, Marcel E, van der Bent, Jessie, Veldkamp, Fleur, Roos, Raymund AC, Achterberg, Wilco P, Lips, Paul
Format Journal Article
LanguageEnglish
Published United States Landes Bioscience 01.06.2013
Subjects
Brief Report
nursing home
vitamin D insufficiency
fall risk
vitamin D deficiency
Huntington disease
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Summary:Vitamin D deficiency and insufficiency are common in older institutionalized people and known to be associated with muscle weakness, impaired balance and increased fall risk. Falls and balance problems are common in people with Huntington disease (HD). Despite this, the prevalence of vitamin D deficiency in patients with manifest HD has never been investigated. Serum 25(OH)D levels were measured in routinely drawn blood samples from 28 Dutch institutionalized patients with manifest Huntington disease. Mean serum 25(OH)D level was 33 nmol/l (SD 15). Twenty-five subjects (89%) were vitamin D deficient or insufficient (25(OH)D < 50 nmol/L). A positive association was found between serum 25(OH)D levels and Functional Ambulation Classification (FAC) scores (p = 0.023).
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ISSN:1938-1980
1938-1972
1938-1980
DOI:10.4161/derm.26135