Autologous Muscle-Derived Nerve Wrap for Prevention of Symptomatic Microneuromas in Primary Nerve Repair

• Published in: Curēus (Palo Alto, CA) Vol. 14; no. 2; p. e22513
• Main Authors: Bruce, William J, Brown, Amanda L, Romanelli, Michael R, Mailey, Brian A
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 23.02.2022; Cureus
• Subjects: Injuries; Pain; Plastic Surgery; Prevention; Scars; Signal transduction; Sutures; regenerative peripheral nerve interface; muscle wrap; neuroma; peripheral nerve; nerve wrap; nerve repair; microneuroma
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.22513

Regeneration of peripheral nerves after repair is incomplete. Painful microneuromas may form at the site of an appropriately performed primary microsurgical nerve repair leading to a persistent Tinel's sign and hypersensitivity in that location. Here, we describe an autologous option using a free muscle-derived nerve wrap with the intent to capture axonal escape at the site of primary nerve coaptation. We demonstrate this technique on a patient undergoing primary nerve repair of a laceration to the superficial branch of the radial nerve using extensor digitorum communis muscle as a donor graft. This has become our preferred technique over commercially available nerve wraps as the muscle wrap is autologous, not limited by cost, and has the potential to limit microneuroma formation at the coaptation site.