Individual resistance to cerebral ischemia and negative effect of emotional stress on the course of this disorder
The ratio of low-activity and high-activity rats differed in autumn, winter, and spring litters. Initially more intensive cerebral blood flow in low-active rats and its more pronounced decrease after common carotid artery occlusion determined their higher sensitivity to cerebral ischemia (compared t...
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Published in | Bulletin of experimental biology and medicine Vol. 137; no. 2; pp. 124 - 127 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English Russian |
Published |
United States
Springer Nature B.V
01.02.2004
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Subjects | |
Online Access | Get full text |
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Summary: | The ratio of low-activity and high-activity rats differed in autumn, winter, and spring litters. Initially more intensive cerebral blood flow in low-active rats and its more pronounced decrease after common carotid artery occlusion determined their higher sensitivity to cerebral ischemia (compared to high-activity animals). After 18-h immobilization stress cerebral blood flow decreased by 10-15%, which abolished the difference in the individual resistance to cerebral ischemia. Independently on emotional resistance, cerebral ischemia was not accompanied by the development of collateral blood flow in the acute period and caused death of 90% rats. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0007-4888 1573-8221 |
DOI: | 10.1023/B:BEBM.0000028119.46097.1a |