Animals in multidimensional space: Interpreting coordinates throughout lexical-semantic features in mild cognitive impairment and control subjects

• Published in: Journal of clinical and experimental neuropsychology Vol. 43; no. 10; pp. 1018 - 1031
• Main Authors: López-Higes, Ramón, Rubio-Valdehita, Susana, Llorente-Morales, Cristina, Sánchez-Beato, Andrea, Delgado-Lima, Alice Helena, Delgado-Losada, María Luisa
• Format: Journal Article
• Language: English
• Published: England Routledge 01.12.2021; Swets & Zeitlinger bv
• Subjects: Aged; Animal cognition; Animals; Cognitive ability; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - psychology; Executive function; Executive Function - physiology; Humans; Language; lexical-semantic features; Memory; mild cognitive impairment; Multidimensional scaling; Neurodegenerative diseases; Neuropsychological Tests; Older people; Regression analysis; semantic map; Semantic verbal fluency; Semantics; Verbal Behavior - physiology; Semantic verbal fluency; mild cognitive impairment; multidimensional scaling; semantic map; lexical-semantic features
• ISSN: 1380-3395; 1744-411X
• DOI: 10.1080/13803395.2022.2057443

Semantic verbal fluency is a useful neuropsychological tool since it involves language and executive abilities that can be impaired in patients with neurodegenerative diseases in comparison to healthy controls. The present study explores retrieve and executive control processes using traditional quantitative and qualitative raw scores and examines the utility of multidimensional scaling combined with linear regression to provide new insights about the underlying semantic network in mild cognitive impairment and in healthy older adults. A total of 165 Spanish older adults, 81 patients and 84 controls, were assessed in different cognitive domains and evoked animal names in one minute. Group differences on fluency raw scores were first explored. Regressions using tests to predict groups' fluency scores were also performed. The 12 animals that had been produced more frequently were selected to perform a multidimensional scaling analysis for each group. Four features related to animal names were extracted from normative studies and then were used as predictors in linear regression to provide an interpretation of the resulting dimensions' coordinates. Patients performed worse on memory and naming and produced a shorter list of animals than controls. In controls, naming and visual memory explained a small part of variance related to the total of animals produced and to the number of switches. Both groups exhibited similar semantic maps. Results suggest that patients' map is influenced by words with a dense associative neighborhood that were acquired at an early age, whereas in controls none of the predictors explained dimensions.