Femtosecond laser fabrication of optofluidic devices for single cell manipulation

In this work we fabricate and validate two optofludic devices for the manipulation and analysis of single cells. The chips are fabricated by femtosecond laser micromachining exploiting the 3D capabilities of the technique and the inherent perfect alignment between microfluidic channels and optical n...

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Bibliographic Details
Published inMATEC Web of Conferences Vol. 32; p. 2001
Main Authors Bragheri, Francesca, Vazquez, Rebeca Martinez, Paiè, Petra, Yang, Tie, Minzioni, Paolo, Cristiani, Ilaria, Osellame, Roberto
Format Journal Article Conference Proceeding
LanguageEnglish
Published Les Ulis EDP Sciences 01.01.2015
Subjects
Chip formation
Elasticity
Electronic devices
Laser machining
Mechanical properties
Micromachining
Optical communication
Optical properties
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Summary:In this work we fabricate and validate two optofludic devices for the manipulation and analysis of single cells. The chips are fabricated by femtosecond laser micromachining exploiting the 3D capabilities of the technique and the inherent perfect alignment between microfluidic channels and optical networks. Both devices have been validated by probing the mechanical properties of different cancer cell lines, which are expected to show different elasticity because of their different metastatic potential.
ISSN:2261-236X
2274-7214
2261-236X
DOI:10.1051/matecconf/20153202001