Phenolic and flavonoid compounds from the fruit shell of Camellia oleifera

• Published in: Journal of asian natural products research Vol. 26; no. 1; pp. 91 - 101
• Main Authors: Shu, Qing, Liu, Yi-Xia, Tang, Yu-Jun, Cheng, Huai-Yu, Wu, Ya-Yu, Xu, Wei, Zhang, Yu-Bo, Zhou, Guang-Xiong
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis 02.01.2024; Taylor & Francis Ltd
• Subjects: anti-inflammatory; anti-RSV; antioxidant; Camellia oleifera; Chemistry; Chemistry, Applied; Chemistry, Medicinal; cytotoxic; Cytotoxicity; Flavonoids; fruit shell; Fruits; Inflammation; Life Sciences & Biomedicine; NMR; Nuclear magnetic resonance; Pharmacology & Pharmacy; Phenolic compounds; Phenols; Physical Sciences; Planar structures; Plant Sciences; Science & Technology; GLYCOSIDES; antioxidant; Camellia oleifera; anti-RSV; LEAVES; anti-inflammatory; ROOTS; fruit shell; SEED CAKE; cytotoxic
• ISSN: 1028-6020; 1477-2213
• DOI: 10.1080/10286020.2023.2293079

A new phenolic compound oleiphenol (1), and a new dihydrochalcone oleifechalcone (2) along with seven known compounds (3-9) were isolated from the fruit shell of Camellia oleifera Abel. The planar structures of compounds 1 and 2 were determined on the basis of extensive spectroscopic analyses (IR, UV, NMR, and HR-ESI-MS) and comparison with literature data. The absolute configurations of the new structures were determined by ECD calculations and chemical methods. In addition, compounds 1-9 underwent a series of pharmacological activity tests, including cytotoxic, anti-inflammatory, anti-RSV and antioxidant activities.