Evolution and sequence analysis of a human Y-chromosomal DNA fragment

• Published in: Journal of molecular evolution Vol. 33; no. 2; p. 133
• Main Authors: Whisenant, E C, Rasheed, B K, Ostrer, H, Bhatnagar, Y M
• Format: Journal Article
• Language: English
• Published: Germany 01.08.1991
• Subjects: Base Sequence; Biological Evolution; Blotting, Southern; Chromosome Deletion; Chromosome Mapping; DNA; Female; Humans; Karyotyping; Male; Molecular Sequence Data; Nucleic Acid Hybridization; Y Chromosome

A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middl...