The influx of uric acid and other purines into everted jejunal sacs of the rat and hamster

• Published in: Canadian journal of physiology and pharmacology Vol. 53; no. 1; p. 113
• Main Authors: Khan, A H, Wilson, S, Crawhall, J C
• Format: Journal Article
• Language: English
• Published: Canada 01.02.1975
• Subjects: Allopurinol - pharmacology; Anaerobiosis; Animals; Biological Transport; Cricetinae; Dinitrophenols - pharmacology; Female; Hypoxanthines - metabolism; In Vitro Techniques; Jejunum - metabolism; Purines - metabolism; Rats; Time Factors; Uric Acid - metabolism; Xanthines - metabolism

The in vitro transport of [2-14-C]uric acid, [8-14-C]hypoxanthine, and [8-14-C]xanthine, each dissolved in Krebs--Ringer bicarbonate buffer, was studied with everted jejunal sacs from rat and hamster. No evidence could be obtained for the development of a concentration gradient between the intracell...