Glycemic control, treatment and complications in patients with type 1 diabetes amongst healthcare settings in Mexico

• Published in: Diabetes research and clinical practice Vol. 180; p. 109038
• Main Authors: Antonio-Villa, Neftali Eduardo, García-Tuomola, Aili, Almeda-Valdes, Paloma, Vidrio-Velázquez, Maricela, Islas-Ortega, Laura, Madrigal-Sanromán, Juan R., Zaballa-Lasso, Carmenmari, Martínez-Ramos-Méndez, Angélica, De la Garza-Hernández, Natalia E., Bustamante-Martínez, Jorge F., González-Galvez, Guillermo, Valadez-Capetillo, Mayra, Sanchez-Ruiz, Karla L., Castillo-Galindo, Carmen, Yepez-Rodríguez, Alicia E., Polanco-Preza, Miguel A., Ceballos-Macías, Jose J., Valenzuela-Montoya, Julio C., Escobedo-Ortiz, Ana R., Ferreira-Hermosillo, Aldo, Rodríguez-Sanchez, Ester, Romero-Zazueta, Alejandro, Miracle-López, Sigfrido, Figueroa-Andrade, Mario H., Faradji, Raquel N.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2021
• Subjects: Healthcare disparities; Metabolic complications; Mexico; Registry; Type 1 diabetes; Metabolic complications; SPB; T1D; DCKD; CGM; Registry; MDI; Healthcare disparities; Type 1 diabetes; RENACED-DT1; SMBG; Mexico; DKA; FPG; HbA1c; BMI
• ISSN: 0168-8227; 1872-8227
• DOI: 10.1016/j.diabres.2021.109038

•Patients living with T1D treated in the public healthcare setting have:•a lower probability for achieving treatment goals.•higher risk for developing T1D chronic complications.•Diabetes knowledge is a mediator in the likelihood of achieving glycemic control.•Healthcare inequalities among private and public settings need to be addressed. Type 1 diabetes (T1D) is a growing chronic disease. Evidence of whether the healthcare setting affects management and glycemic control is scarce. We evaluate outcomes in patients with T1D in private and public healthcare settings in Mexico, registered in the National T1D Registry in Mexico (RENACED-DT1). Biochemical parameters, diabetes education, and treatment were analyzed considering the data registered in the last visit. Development of chronic complications was determined during follow-up. We included 1,603 patients; 71.5% (n = 1,146) registered in the public system, and 28.5% (n = 457) in a private institution. Patients in the public setting had higher HbA1c (8.6%, IQR: 7.3%-10.5% vs 7.7%, IQR: 7.0%-8.8%; p < 0.001). Indicators of diabetes education, glucose monitoring, and use of insulin-pumps were lower in the public setting. Patients in the public setting were at higher risk of diabetic chronic kidney disease, retinopathy, and neuropathy. Diabetes knowledge was a mediator between type of healthcare setting and the likelihood of achieving glycemic control. Patients registered in public healthcare settings have an adverse metabolic profile and higher risk of complications. Social factors need to be addressed in order to implement multidisciplinary measures focused on diabetes education for patients with T1D in Mexico.