Effects of Contact lens-induced hypoxia on the physiology of the corneal endothelium
Contact lens wear can cause a number of physiological changes in the cornea. Two areas of interest in my laboratory have been contact lens effects on the endothelium and, more recently, the role of metabolic activity in predicting corneal swelling. The first part of this review focuses on the functi...
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Published in | Optometry and vision science Vol. 78; no. 11; pp. 783 - 790 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Hagerstown, MD
Lippincott Williams & Wilkins
01.11.2001
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Subjects | |
Online Access | Get full text |
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Summary: | Contact lens wear can cause a number of physiological changes in the cornea. Two areas of interest in my laboratory have been contact lens effects on the endothelium and, more recently, the role of metabolic activity in predicting corneal swelling. The first part of this review focuses on the function of the corneal endothelium, the nature of its fluid pump, and the effects of contact lens-induced hypoxia and corneal pH changes on corneal endothelial function. In the second part, the etiology of hypoxia-induced corneal swelling is reviewed in relation to new studies on the causes of intersubject corneal swelling variability. The results indicate that corneal swelling is influenced by both corneal metabolic activity and endothelial function. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 1040-5488 1538-9235 |
DOI: | 10.1097/00006324-200111000-00008 |