Hyposplenism and Gastrointestinal Diseases: Significance and Mechanisms
Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders. Summary: The mechanisms of hyposplenism are poorly unde...
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| Published in | Digestive diseases (Basel) Vol. 40; no. 3; pp. 290 - 298 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
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Basel, Switzerland
01.01.2022
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| Abstract | Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders. Summary: The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management. Key Messages: Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination. |
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| AbstractList | Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders.
The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management.
Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination. Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders. Summary: The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management. Key Messages: Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination. |
| Author | Mathur, Abhinav Vickers, Mark A. McLean, Mairi H. Cao, Huan |
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| Copyright | 2021 The Author(s). Published by S. Karger AG, Basel 2021 The Author(s). Published by S. Karger AG, Basel. |
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| Issue | 3 |
| Keywords | Hyposplenism Spleen Inflammatory bowel disease Coeliac disease |
| Language | English |
| License | This article is licensed under the Creative Commons Attribution 4.0 International License (CC BY). Usage, derivative works and distribution are permitted provided that proper credit is given to the author and the original publisher. 2021 The Author(s). Published by S. Karger AG, Basel. |
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| Snippet | Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases,... Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is... |
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| Title | Hyposplenism and Gastrointestinal Diseases: Significance and Mechanisms |
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