Long-term outcome and quality of life of dogs that developed neurologic signs after surgical treatment of a congenital portosystemic shunt: 50 cases (2005-2020)

• Published in: Journal of the American Veterinary Medical Association Vol. 260; no. 3; p. 326
• Main Authors: Escribano Carrera, Antía, Morrissey, Anya M, Lipscomb, Victoria J, Tivers, Michael S, Chan, Alex, Lisa Pinel Pisco, Vera, Anderson, Davina M, Fox-Alvarez, William A, Kirby Dvm, Barbara M, de Rooster, Hilde, Nurra, Genziana, Yool, Donald A, Singh, Ameet, Olive, Melanie, Phillipe Billet, Jean, Mullins, Ronan A
• Format: Journal Article
• Language: English
• Published: United States 01.02.2022
• ISSN: 1943-569X
• DOI: 10.2460/javma.20.11.0606

To determine survival time and quality of life of dogs that developed postattenuation neurologic signs (PANS) after surgical treatment of a single congenital portosystemic shunt and survived at least 30 days and identify whether neurologic signs present at the time of discharge would resolve or reoccur. 50 client-owned dogs. Medical records were retrospectively reviewed, and follow-up data relating to neurologic signs and seizure activity were obtained. Owners were asked to complete a questionnaire related to the presence of neurologic signs, including seizures, and their dog's quality of life. Thirty of the 50 (60%) dogs had postattenuation seizures with or without other nonseizure neurologic signs, and 20 (40%) had neurologic signs other than seizures. Neurologic signs had fully resolved by the time of discharge in 24 (48%) dogs. Signs resolved in 18 of the remaining 26 (69%) dogs that still had PANS other than seizures at the time of discharge. Seizures reoccurred in 15 of the 30 dogs that had postattenuation seizures. Twenty-seven of 33 (82%) owners graded their dog's long-term (> 30 days after surgery) quality-of-life as high. Forty-five (90%) dogs survived > 6 months. Most (29/43 [67%]) neurologic signs (other than seizures) present at the time of hospital discharge resolved. Findings highlighted that survival times of > 6 months and a high QOL can be achieved in most dogs with PANS that survive at least 30 days. Most neurologic signs other than seizures resolved within 1 month postoperatively. Half of the dogs with postattenuation seizures had a reoccurrence.