The First Case Report of a Systemic Allergy to OnabotulinumtoxinA (Botox) in a Healthy Patient

To the authors' knowledge, this is the first report of an allergy to onabotulinumtoxinA. The 43-year-old woman experienced severe itching after injection of Botox and Juvéderm. Results of prick and patch testing confirmed a T-cell-mediated allergy to Botox. This case can aid in the evaluation o...

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Bibliographic Details
Published inAesthetic surgery journal Vol. 34; no. 5; p. 766
Main Authors Rosenfield, Lorne King, Kardassakis, Dean George, Tsia, Kristen Anne, Stayner, Grace
Format Journal Article
LanguageEnglish
Published England 01.07.2014
Subjects
Acetylcholine Release Inhibitors - administration & dosage
Acetylcholine Release Inhibitors - adverse effects
Adult
Anti-Allergic Agents - therapeutic use
Botulinum Toxins, Type A - administration & dosage
Botulinum Toxins, Type A - adverse effects
Drug Eruptions - diagnosis
Drug Eruptions - drug therapy
Drug Eruptions - etiology
Drug Eruptions - immunology
Female
Humans
Intradermal Tests
Patch Tests
T-Lymphocytes - drug effects
T-Lymphocytes - immunology
Treatment Outcome
contact dermatitis
systemic allergy
hypersensitivity
onabotulinumtoxinA
Botox Cosmetic
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Summary:To the authors' knowledge, this is the first report of an allergy to onabotulinumtoxinA. The 43-year-old woman experienced severe itching after injection of Botox and Juvéderm. Results of prick and patch testing confirmed a T-cell-mediated allergy to Botox. This case can aid in the evaluation of suspected allergies to Botox. 5.
ISSN:1527-330X
DOI:10.1177/1090820X14532648