Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus

• Published in: Translational vision science & technology Vol. 11; no. 3; p. 19
• Main Authors: Alejandre, Nicolas, Pérez-Merino, Pablo, Velarde, Gonzalo, Jiménez-Alfaro, Ignacio, Marcos, Susana
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 15.03.2022
• Subjects: Astigmatism - surgery; Corneal Stroma - diagnostic imaging; Corneal Stroma - surgery; Corneal Topography; Eye, Artificial; Humans; Keratoconus - surgery; Prosthesis Implantation - methods; Refraction, Ocular; Visual Acuity
• ISSN: 2164-2591; 2164-2591
• DOI: 10.1167/tvst.11.3.19

The purpose of this study was to assess the impact of different intracorneal ring segments (ICRS) combinations on corneal morphology and visual performance on patients with keratoconus. A total of 124 eyes from 96 patients who underwent ICRS surgery were analyzed and classified into 7 groups based on ICRS disposition and the diameter of the surgical zone (5- and 6-mm). Pre- and postoperative complete ophthalmological examinations were conducted. Corneal geometry, volume, and symmetry were studied. Zernike polynomials were used to build a virtual ray-tracing model to evaluate optical aberrations and the Visual Strehl (VS). ICRS induced significant flattening across the cornea, being more pronounced on the anterior (+0.38 mm, P < 0.001) than on the posterior (+0.15 mm, P < 0.001) corneal radius. Asphericity experienced a larger change for a 6-mm surgical zone diameter (from -1.23 ± 1.1 to -1.86 ± 1.2, P < 0.001) than for a 5-mm zone (from -1.99 ± 1.1 to -2.10 ± 1.5, P = 0.536). Mean astigmatism was reduced by 2.05 D (P < 0.001). Combination four was the most effective in reducing astigmatism. Coma decreased by 30% on average and combination one produced an average reduction by 51% (P < 0.05). Patients experienced significant improvement in visual performance, best corrected visual acuity increased from 0.57 ± 0.21 to 0.69 ± 0.21 and VS changed from 0.049 ± 0.02 to 0.065 ± 0.041. ICRS combinations implanted within 5 mm diameter zone are more effective in flattening the cornea, whereas those implanted on 6 mm diameter are as effective in reducing astigmatism and are a good choice if the asymmetry and the intended flattening are smaller. Combinations with asymmetrical implants are the best option to regularize corneal surface. This study uses methods and metrics of optical research applied to daily clinical practice.