Loss of ACTH biological activity in plasma during extraction with a commercial radioimmunoassay kit

The process used for extracting adrenocorticotropic hormone (ACTH) from plasma in the Searle ACTH immunoassay kit involves a loss of 70-100% of the biological activity of the ACTH.

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Bibliographic Details
Published inCanadian journal of physiology and pharmacology Vol. 54; no. 2; p. 170
Main Author Cowan, J S
Format Journal Article
LanguageEnglish
Published Canada 01.04.1976
Subjects
Adrenocorticotropic Hormone - blood
Adrenocorticotropic Hormone - isolation & purification
Animals
Dogs
Female
Humans
Male
Radioimmunoassay - instrumentation
Radioimmunoassay - methods
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Summary:The process used for extracting adrenocorticotropic hormone (ACTH) from plasma in the Searle ACTH immunoassay kit involves a loss of 70-100% of the biological activity of the ACTH.
ISSN:0008-4212
DOI:10.1139/y76-028