Discussion of “Sarcopenia is not associated with morbidity, mortality, or recurrence after esophagectomy for cancer”

The authors have chosen the presence or absence of sarcopenia as a potentially useful predictive tool in risk assessment for esophagectomy, as it has been found to be predictive of perioperative complications, mortality, and decreased survival for other solid tumors. While the authors have quoted 1...

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Bibliographic Details
Published inThe American journal of surgery Vol. 215; no. 5; p. 818
Main Author Aye MD, Ralph W.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.2018
Elsevier Limited
Subjects
Cancer
Esophageal cancer
Esophageal Neoplasms - surgery
Esophagectomy
Esophagus
Gastrointestinal surgery
Humans
Morbidity
Mortality
Neoplasm Recurrence, Local
Risk assessment
Sarcopenia
Studies
Surgery
Surgical outcomes
Survival
Toxicity
Tumors
United States > US
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Summary:The authors have chosen the presence or absence of sarcopenia as a potentially useful predictive tool in risk assessment for esophagectomy, as it has been found to be predictive of perioperative complications, mortality, and decreased survival for other solid tumors. While the authors have quoted 1 study showing no difference in survival there are at least 7 studies evaluating sarcopenia and esophageal cancer, 6 of which showed at least 1 parameter having worse outcomes with sarcopenia: 4 found decreased survival, 3 found worse surgical outcomes, and 2 found increased toxicity from neoadjuvant therapy prior to surgery. [...]though there is no statistical difference in overall or disease-free survivals, the curves diverge in favor of the non-sarcopenia group, so perhaps this is a matter of insufficient numbers as they allude to.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2017.11.056