Activity-dependent plasticity of spinal locomotion: implications for sensory processing

The lumbosacral spinal cord of mammals contains the neural circuitry capable of generating full weight-bearing locomotion of the hind limbs without any supraspinal input. One or more interventions, for example, pharmacological, epidural stimulation, and/or locomotor training, however, are necessary...

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Bibliographic Details
Published inExercise and sport sciences reviews Vol. 37; no. 4; p. 171
Main Authors Edgerton, V Reggie, Roy, Roland R
Format Journal Article
LanguageEnglish
Published United States 01.10.2009
Subjects
Animals
Cats
Feedback, Sensory
Interneurons - physiology
Learning - physiology
Locomotion - physiology
Motor Activity - physiology
Nerve Net - physiology
Neuronal Plasticity
Rats
Spinal Cord Injuries - rehabilitation
Weight-Bearing - physiology
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Summary:The lumbosacral spinal cord of mammals contains the neural circuitry capable of generating full weight-bearing locomotion of the hind limbs without any supraspinal input. One or more interventions, for example, pharmacological, epidural stimulation, and/or locomotor training, however, are necessary to gain access to and modulate the properties of this circuitry and to facilitate recovery of full weight-bearing locomotion after spinal cord injury.
ISSN:1538-3008
DOI:10.1097/JES.0b013e3181b7b932