SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group

SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely impl...

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Bibliographic Details
Published inMedical journal. Armed Forces India
Main Authors Daryani, Hitesh, Jamal, Ahmed, Bhat, Vivek, Mukund, Bal
Format Journal Article
LanguageEnglish
Published India Elsevier B.V 26.02.2023
Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd
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Summary:SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely implicated as a causal factor for hemolytic anemia in children. We present a 12-year-old male child who presented in congestive cardiac failure due to severe hemolytic anemia caused by SARS-CoV-2, with hemoglobin falling to a nadir of 1.8 g/dL. Child was diagnosed as a case of autoimmune hemolytic anemia and managed with supportive management and long-term steroids. This case highlights one of the lesser known effects of the virus, causing severe hemolysis and the role of steroids in its treatment.
ISSN:0377-1237
2213-4743
DOI:10.1016/j.mjafi.2022.12.016