Preliminary research on dual-energy X-ray phase-contrast imaging

Dual-energy X-ray absorptiometry（DEXA） has been widely applied to measure the bone mineral density（BMD） and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging（...

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Published inChinese physics C Vol. 40; no. 4; pp. 141 - 148
Main Author 韩华杰 王圣浩 高昆 王志立 张灿 杨萌 张凯 朱佩平
Format Journal Article
LanguageEnglish
Published United States IOP Publishing 01.04.2016
Subjects
Absorption
area density
Bones
Density
dual-energy
Imaging
INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
Mathematical analysis
phase-contrast
RADIOLOGY AND NUCLEAR MEDICINE
Simulation
Soft tissues
X-ray imaging
X-rays
双能X射线
密度测量
成像
理论计算值
相位衬度
组织成分
能量法
计算面积
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Summary:Dual-energy X-ray absorptiometry（DEXA） has been widely applied to measure the bone mineral density（BMD） and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging（XPCI） shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials.
Bibliography:11-5641/O4
DEXA refraction replace grating pixel Talbot sorption downstream precise listed
Dual-energy X-ray absorptiometry（DEXA） has been widely applied to measure the bone mineral density（BMD） and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging（XPCI） shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials.
Hua-Jie Han, Sheng-Hao Wang, Kun Gao, Zhi-Li Wang, Can Zhang,Meng Yang, Kai Zhang, Pei-Ping Zhu（1 National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230027, China 2 School of Engineering Science, University of Science and Technology of China, Hefei 230027, China 3 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China）
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
National Natural Science Foundation of China (NSFC)
AC02-05CH11231
USDOE Office of Science (SC)
ISSN:1674-1137
0254-3052
DOI:10.1088/1674-1137/40/4/048201