Identification of antioxidant activity of two new aromatic ring butyrolactone derivatives from Dictamnus dasycarpus Turcz

• Published in: Chinese journal of natural medicines Vol. 14; no. 11; pp. 876 - 880
• Main Authors: GUO, Li-Na, PEI, Yue-Hu, XIE, Fei-Xiang, LIU, Lei, CONG, Huan, CUI, Hong-Xia, WANG, Xiao-Li, LI, Wen-Jing, JIAN, Bai-Yu, LIU, Ji-Cheng
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.11.2016
• Subjects: 4-Butyrolactone - chemistry; 4-Butyrolactone - isolation & purification; Antioxidant activity; Antioxidants - chemistry; Antioxidants - isolation & purification; Dasycarpusphenol acid A; Dasycarpusphenol acid B; Dictamnus - chemistry; Dictamnus dasycarpus; Molecular Structure; Plant Bark - chemistry; Plant Extracts - chemistry; Plant Extracts - isolation & purification; Dasycarpusphenol acid A; Dictamnus dasycarpus; Antioxidant activity; Dasycarpusphenol acid B
• ISSN: 1875-5364; 1875-5364
• DOI: 10.1016/S1875-5364(16)30105-4

The present study carried out a phytochemical investigation on the root barks of Dictamnus dasycarpus Turcz, leading to the isolation and characterization of two new aromatic ring butyrolactone derivatives, dasycarpusphenol acid A (1) and dasycarpusphenol acid B (2). Their structures were elucidated by using spectroscopic techniques and HR-FAB-MS. Compounds 1 and 2 exhibited antioxidant activity, with their IC50 values being 28.95 and 41.76 mg·mL−1, respectively.