Metrology in health: challenges and solutions in infusion therapy and diagnostics

The significance of Metrology in infusion therapy and diagnostics, both critical in health care safety and quality, is discussed in this article. Although infusion therapy is the most used form of drug administration, infusion errors are often made with reported dramatic effects in different applica...

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Published inBiomedizinische Technik Vol. 68; no. 1; pp. 3 - 12
Main Authors Metaxiotou, Zoe, Bissig, Hugo, Batista, Elsa, do Céu Ferreira, Maria, Timmerman, Annemoon
Format Journal Article
LanguageEnglish
Published Germany De Gruyter 23.02.2023
Walter de Gruyter GmbH
Subjects
Commercialization
COVID-19
COVID-19 Testing
diagnostics
dissemination
Dosage
Drug administration
Drug delivery
Drug Delivery Systems - methods
Drug dosages
Flow velocity
health
Health care
Humans
Infectious diseases
infusion
Intravenous therapy
Metrology
microfluidics
Morbidity
Public health
Therapy
standards
diagnostics
infusion
dissemination
health
metrology
microfluidics
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Summary:The significance of Metrology in infusion therapy and diagnostics, both critical in health care safety and quality, is discussed in this article. Although infusion therapy is the most used form of drug administration, infusion errors are often made with reported dramatic effects in different applications, especially in neonatology. Adverse incidents, morbidity, and mortality have often been traced back to poor or inaccurate dosing. For critical infusion applications to vulnerable patients, well-controlled medication administration might be accomplished by improved dosing accuracy, traceable measurement of volume, flow, and pressure in existing drug delivery devices and in-line sensors operating at very low flow rates. To this end, the contribution of recently upgraded metrological infrastructures in European Metrology Institutes to a safer infusion therapy in health care is described in detail. Diagnostics, on the other hand is a sector characterized by rapid developments further triggered recently by the necessity for the management and prevention of infectious diseases like COVID-19. In this context, the impact of metrology in future large-scale commercialization of next generation diagnostics (e.g., point-of-care) is highlighted. Moreover, the latest contributions of Metrology in the development of traceable testing methods and protocols to ensure the sensitivity and accuracy of these devices are described.
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ISSN:0013-5585
1862-278X
DOI:10.1515/bmt-2022-0045