Problematic clinical trials in thyroid cancer: the issue of papillary carcinoma and observational approaches

• Published in: International Journal of Endocrine Oncology Vol. 4; no. 3; pp. 127 - 136
• Main Authors: Rosenthal, M Sara, Ain, Kenneth B, Angelos, Peter, Hatanaka, Ryoko, Motojima, Masaru
• Format: Journal Article
• Language: English; Japanese
• Published: London Future Medicine Ltd 01.08.2017; Informa UK Limited
• Subjects: Blood & organ donations; Cancer therapies; Cervical cancer; clinical ethics; clinical trials; Diabetes; Ethics; Human subjects; Hypertension; Iodine; Lymphatic system; Medical prognosis; Metastasis; observational protocols; Research ethics; Surgery; Surveillance; Thyroid cancer; Tumors; United States > US; Japan; India

We describe the clinical ethics problem of American thyroid cancer patients being offered 'observation' instead of the USA standard of care with questionable informed consent. This problem arose because some American practitioners misinterpreted 1990s Japanese studies. American proponents...