Protein Microarrays for Cancer Diagnostics and Therapy

In this postgenomic age, cancer will be understood in intricate detail beyond the genomic level. New technologies are emerging that allow global proteomic level characterization, profiling and understanding. One of the most exciting emerging technologies of cancer proteomics is protein microarray. I...

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Bibliographic Details
Published inMedical principles and practice Vol. 19; no. 4; pp. 247 - 254
Main Author Lin, Jimmy Cheng-Ho
Format Journal Article
LanguageEnglish
Published Basel, Switzerland 01.01.2010
Subjects
Biomarkers, Tumor
Humans
Mass Spectrometry
Neoplasms - diagnosis
Neoplasms - drug therapy
Neoplasms - metabolism
Prognosis
Protein Array Analysis - methods
Proteomics
Review
Protein array
Mass spectrometry
Proteomics
Cancer
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Summary:In this postgenomic age, cancer will be understood in intricate detail beyond the genomic level. New technologies are emerging that allow global proteomic level characterization, profiling and understanding. One of the most exciting emerging technologies of cancer proteomics is protein microarray. In this review, the different types of protein microarrays are discussed, including the methods, challenges and techniques of each type. Subsequently, the application of these specific methods to cancer diagnosis, prognosis and therapy will be overviewed, providing a general review of current methods, and proposing how protein arrays will help shape the future of oncoproteomics.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1011-7571
1423-0151
DOI:10.1159/000312709