A primary primitive neuroectodermal tumor of the central nervous system in a 51-year-old woman: a case report and literature review

• Published in: Medicina (Kaunas, Lithuania) Vol. 47; no. 8; pp. 440 - 445
• Main Authors: Ašmonienė, Virginija, Skiriutė, Daina, Gudinavičienė, Inga, Tamašauskas, Šarūnas, Skauminas, Kęstutis, Deltuva, Vytenis Pranas, Tamašauskas, Arimantas
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.2011
• Subjects: Brain Neoplasms - diagnosis; Brain Neoplasms - genetics; Brain Neoplasms - pathology; Cyclin-Dependent Kinase Inhibitor p16 - genetics; Exons; Female; Gene Deletion; Homozygote; Humans; Magnetic Resonance Imaging; Middle Aged; Neuroectodermal Tumors, Primitive - diagnosis; Neuroectodermal Tumors, Primitive - genetics; Neuroectodermal Tumors, Primitive - pathology; Tumor Suppressor Protein p14ARF - genetics
• ISSN: 1648-9144; 1648-9144
• DOI: 10.3390/medicina47080060

Primitive neuroectodermal tumors are a group of rare, aggressive, and highly malignant embryonal tumors of unknown etiology of the central and peripheral nervous systems. It is a term for a group of small round cell tumors thought to be derived from fetal neuroectodermal precursor cells. Primitive neuroectodermal tumor is usually described as a tumor of children younger than 15 years and is very rare in adults. The article presents a short literature review and a rare case of a primary primitive neuroectodermal tumor of the central nervous system diagnosed in a 51-year-old woman.