Visible-light-induced decarboxylative acylation of quinoxalin-2(1)-ones with α-oxo carboxylic acids under metal-, strong oxidant- and external photocatalyst-free conditions

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 22; no. 5; pp. 172 - 1725
• Main Authors: Xie, Long-Yong, Bai, You-Shu, Xu, Xiang-Qin, Peng, Xia, Tang, Hai-Shan, Huang, Ying, Lin, Ying-Wu, Cao, Zhong, He, Wei-Min
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 09.03.2020; Royal Society of Chemistry
• Subjects: Acylation; air; Air temperature; ambient temperature; Carboxylic acids; Catalysts; Chemistry; Chemistry, Multidisciplinary; Green & Sustainable Science & Technology; Green chemistry; Light effects; Oxidants; Oxidizing agents; Physical Sciences; Room temperature; Science & Technology; Science & Technology - Other Topics; wastes; ALCOHOLS; THIOLS; AMINATION; QUINOXALIN-2(H)-ONES; QUINOXALINONES; PHOSPHONATION; ARYLATION; 3-ARYLATION; C-H TRIFLUOROMETHYLATION; CYCLIZATION
• ISSN: 1463-9262; 1463-9270; 1463-9270
• DOI: 10.1039/c9gc03899j

A mild and eco-friendly visible-light-induced decarboxylative acylation of quinoxalin-2(1 H )-ones and α-oxo carboxylic acids with ambient air as the sole oxidant at room temperature was established. The reaction proceeded efficiently without any metal catalysts, strong oxidants or external-photosensitizers, ultimately reducing the generation of waste. An eco-friendly visible-light-induced decarboxylative acylation of quinoxalin-2(1 H )-ones and α-oxo carboxylic acids with air as the oxidant under external-photocatalyst-free conditions was established.