Use of the Allium cepa Model to Assess the Cytogenotoxicity of Luffariella herdmani Marine Sponge Extract

• Published in: Alternatives to laboratory animals Vol. 51; no. 3; p. 175
• Main Authors: Kuruppuarachchi, Sashini U, Jayawardena, Uthpala A, Gunathilake, Varuni K
• Format: Journal Article
• Language: English
• Published: England 01.05.2023
• Subjects: Animals; Chromosome Aberrations; Meristem; Onions; Plant Roots; Porifera; Allium cepa model; chromosomal aberrations; non-animal alternatives; marine sponge extract; Luffariella herdmani; cytogenotoxicity

Marine sponge extracts are known to contain potentially toxic compounds that have biological activities of possible pharmacological interest. Thus, it is vital that biological models are used for the preliminary toxicity screening of such extracts. The present study reports the use of , a low-cost p...