GOLD DNA-CONJUGATES: ION SPECIFIC SELF-ASSEMBLY OF GOLD NANOPARTICLES VIA THE DG-QUARTET

The Oxytricha telomere DNA hairpin 5′-d(G4T4G4) immobilized on 13 nm gold nanoparticles forms a supramolecular assembly via dG-quartets, as determined by the color change and by SEM. The aggregation is ion-dependent and selective for sodium ions. K + is less efficient while Li + and Cs + do not driv...

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Published inNucleosides, nucleotides & nucleic acids Vol. 24; no. 5-7; pp. 843 - 846
Main Authors Seela, Frank, Jawalekar, Anup, Chi, Lifeng, Zhong, Dingyong, Fuchs, Harald
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis Group 01.01.2005
Subjects
Base Sequence
DNA
DNA - chemistry
G-Quartet
Gold - chemistry
Gold-Nanoparticles
Guanine - chemistry
Ions
Macromolecular Substances
Microscopy, Electron, Scanning
Molecular Conformation
Molecular Sequence Data
Nanostructures - chemistry
Nucleic Acid Conformation
Nucleic Acid Denaturation
Nucleic Acid Heteroduplexes
Potassium - chemistry
Self-Assembly
Sodium - chemistry
Telomere - ultrastructure
Ultraviolet Rays
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Summary:The Oxytricha telomere DNA hairpin 5′-d(G4T4G4) immobilized on 13 nm gold nanoparticles forms a supramolecular assembly via dG-quartets, as determined by the color change and by SEM. The aggregation is ion-dependent and selective for sodium ions. K + is less efficient while Li + and Cs + do not drive the aggregation. This work is the first effort exploring the use of secondary structures of DNA (quadruplexes) for producing self-assemblies of gold nanoparticles.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1525-7770
1532-2335
DOI:10.1081/NCN-200060322