Fluorescent probe for mercury ion imaging analysis: Strategies and applications

• Published in: Chemical engineering journal (Lausanne, Switzerland : 1996) Vol. 406; p. 127166
• Main Authors: Wang, Yue, Zhang, Li, Han, Xiaoyue, Zhang, Liangwei, Wang, Xiaoyan, Chen, Lingxin
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.02.2021
• Subjects: Environmental analysis; Fluorescence analysis; Fluorescent probe; Mercury ions; Fluorescence analysis; Mercury ions; Environmental analysis; Fluorescent probe
• ISSN: 1385-8947; 1873-3212
• DOI: 10.1016/j.cej.2020.127166

[Display omitted] •The response type and design strategies of fluorescent probes for Hg2+ sensing are reviewed.•The performance of fluorescent probes for Hg2+ analysis are described in detail.•The applications of fluorescent probes for Hg2+ detection in biological and environmental samples are summarized.•The challenges and prospects of fluorescent probes for Hg2+ sensing are proposed.•Orienting new design strategies and applications expanding are recommended. Environmental pollution problem, especially mercury ions (Hg2+) pollution, seriously threatens the organism health. Numerous researches have revealed that even extremely low concentration of Hg2+ can severely damage the organisms. Therefore, it is essential for real-time detection of Hg2+. Fluorescent probe technology with great advantages has become the preferred technique for environmental detection and in vivo analysis of Hg2+. In recent years, lots of contributions have been committed to designing and synthesizing novel fluorescent probes for environmental pollutant Hg2+ analysis. In this feature article, we review the recent advances in fluorescent probes for Hg2+ analysis, focusing on probe response modes, including signal-decreased fluorescent probes, signal-enhanced fluorescent probes, ratiometric fluorescent probes as well as fluorescent probes for Hg2+ and other species analysis. Moreover, the design strategies, performance and applications of fluorescent probes are summarized in detail. Challenges and prospects for fluorescent probe are proposed, orienting new design strategies and applications expanding.