Pru p 3 sublingual immunotherapy ultra-rush protocol is safe and clinically effective

Sublingual immunotherapy (SLIT) with Pru p 3 can prevent severe allergic reactions to LTP-containing foods, but the standard initiation protocol is time-consuming. Establish the safety of a novel ultra-rush initiation protocol for SLIT with Pru p 3. Prospective study comparing the side effects of th...

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Published inEuropean annals of allergy and clinical immunology Vol. 51; no. 5; pp. 206 - 212
Main Authors Moura, A L, Pereira, C, Regateiro, F S, Azevedo, J, Todo Bom, A, Carrapatoso, I
Format Journal Article
LanguageEnglish
Published Italy 16.09.2019
Subjects
peach allergy
sublingual immunotherapy
LTP syndrome
ultra-rush protocol
Pru p 3
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Summary:Sublingual immunotherapy (SLIT) with Pru p 3 can prevent severe allergic reactions to LTP-containing foods, but the standard initiation protocol is time-consuming. Establish the safety of a novel ultra-rush initiation protocol for SLIT with Pru p 3. Prospective study comparing the side effects of the standard vs novel ultra-rush initiation protocols of SLIT with Pru p 3 in patients with anaphylaxis to LTP. Fifteen patients were included (standard initiation, 5; ultra-rush initiation, 10), 80% females. All patients had oropharyngeal pruritus during initiation, 80% with spontaneous recovery, but no other gastro-intestinal, respiratory, cutaneous or systemic side effects occurred in any patient of both groups. The novel ultra-rush protocol halved the build-up time without increasing side effects.
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ISSN:1764-1489
1764-1489
DOI:10.23822/EurAnnACI.1764-1489.99