HISTOCOMPATIBILITY ANTIGENS IN PATIENTS WITH SPINAL CORD INJURY OR CEREBRAL DAMAGE COMPLICATED BY HETEROTOPIC OSSIFICATION

SUMMARY The frequency of HLA antigens of the A and B loci in 21 patients with spinal cord injury and three patients with cerebral damage complicated by heterotopic ossification was compared with the frequency seen in 740 healthy controls. No significant difference in the frequency of HLA antigens wa...

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Published inRheumatology (Oxford, England) Vol. 19; no. 2; pp. 97 - 99
Main Authors HUNTER, T., DUBO, H. I. C., HILDAHL, C. R., SMITH, N. J., SCHROEDER, M. L.
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.05.1980
Subjects
Adult
Aged
Cerebral Palsy - complications
Female
Histocompatibility Antigens - immunology
Humans
Male
Middle Aged
Ossification, Heterotopic - etiology
Ossification, Heterotopic - immunology
Spinal Cord Injuries - complications
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Summary:SUMMARY The frequency of HLA antigens of the A and B loci in 21 patients with spinal cord injury and three patients with cerebral damage complicated by heterotopic ossification was compared with the frequency seen in 740 healthy controls. No significant difference in the frequency of HLA antigens was detected between the two groups. In contrast to a previous study, when the spinal cord injury patients complicated by heterotopic ossification were compared to healthy controls, there was no increase in the frequency of HLA B18. Further studies of the HLA system in patients with heterotopic ossification are warranted.
Bibliography:Requests for reprints to Dr. Thomas Hunter, University of Manitoba, Rheumatic Disease Unit, Health Sciences Centre, 800 Sherbrook Street, Winnipeg, Manitoba R3A 1M4.
ark:/67375/HXZ-6CB8LLVJ-2
istex:7C654FC65679D2A0604AF09FCFF2FEF48D6E4477
Presented in part at the Annual Meeting of the Royal College of Physicians and Surgeons of Canada, Vancouver 1978.
ArticleID:19.2.97
ISSN:1462-0324
0300-3396
1462-0332
DOI:10.1093/rheumatology/19.2.97