Primary Diffuse Large B-cell Lymphoma of the Sigmoid Colon

• Published in: Curēus (Palo Alto, CA) Vol. 11; no. 6; p. e5048
• Main Authors: Haddad, Ibrahim, El Kurdi, Bara, El Iskandarani, Mahmoud, Babar, Sumbal, Young, Mark
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 30.06.2019; Cureus
• Subjects: Abdomen; Age; Biopsy; Bone marrow; Case reports; Chemotherapy; Colon; Colonoscopy; Colorectal cancer; Constipation; Gastroenterology; Gastrointestinal cancer; Gene expression; Immunotherapy; Internal Medicine; Lymphoma; Medicine; NMR; Nuclear magnetic resonance; Oncology; Pain; Patients; Radiation therapy; Transplants & implants; United States > US; primary diffuse large b-cell lymphoma of the colon; large colon; primary gastrointestinal lymphoma; primary colorectal lymphoma
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.5048

Primary gastrointestinal lymphoma is the most common type of extra-nodal lymphoma, representing about 30%-50% of all extra-nodal involvement. The stomach is the most common site, with the colon and rectum accounting for a minority of occurrences. Primary colorectal lymphoma is uncommon, representing only 0.3% of all large intestinal malignancies and approximately 3% of gastrointestinal (GI) lymphomas, with the majority of these being B-cell non-Hodgkin lymphoma and diffuse large B-cell lymphoma (DLBCL) being the most common subtype. We present a case of an 85-year-old male who presented with symptoms suggestive of bowel obstruction, who, after further evaluation, was diagnosed with primary non-Hodgkin lymphoma of the colon, DLBCL subtype.