Synthesis of a designed sesquiterpenoid that forms useful composites with peptides and related oligomers

Efficient desymmetrization of isophthalaldehyde allows a scalable asymmetric synthesis of cinnamylated sesquiterpenoid 1. We have shown 1 forms useful, property-altered composites with peptides and related oligomers. The current synthesis promises to expand those efforts considerably. Efficient desy...

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Bibliographic Details
Published inTetrahedron letters Vol. 52; no. 6; pp. 653 - 654
Main Authors Lawson, Kenneth V., Rose, Tristan E., Harran, Patrick G.
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 09.02.2011
Elsevier
Subjects
Asymmetry
Chemistry
Chemistry, Organic
Oligomers
Peptides
Physical Sciences
Science & Technology
Synthesis (chemistry)
Tetrahedrons
ALLYLIC ALCOHOLS
ALDEHYDES
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Summary:Efficient desymmetrization of isophthalaldehyde allows a scalable asymmetric synthesis of cinnamylated sesquiterpenoid 1. We have shown 1 forms useful, property-altered composites with peptides and related oligomers. The current synthesis promises to expand those efforts considerably. Efficient desymmetrization of isophthalaldehyde allows a scalable asymmetric synthesis of cinnamylated sesquiterpenoid 1. We have shown that 1 forms useful, property-altered composites with peptides and related oligomers. The current synthesis promises to expand those efforts considerably.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2010.11.083