Preparation of surface molecularly imprinted polymers with Fe3O4/ZIF-8 as carrier for detection of Dimethoate in cabbage

• Published in: Journal of Chromatography A Vol. 1722; p. 464859
• Main Authors: Tian, Yanbo, Majid, Abdul, Zhang, Yuewei, Tan, Liju, Li, Huiru, Wang, Na, Wang, Jiangtao
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 10.05.2024
• Subjects: Dimethoate; Food safety; Magnetic solid phase extraction; Metal-organic complex; Molecularly imprinted polymer; Food safety; Magnetic solid phase extraction; Dimethoate; Molecularly imprinted polymer; Metal-organic complex
• ISSN: 0021-9673
• DOI: 10.1016/j.chroma.2024.464859

•Density functional theory simulation was utilized to select the optimal functional monomer.•Magnetic molecularly imprinted polymer (MMIP) was prepared on the surface of Fe3O4/ZIF-8 by surface imprinting technique.•The theoretical specific adsorption capacity of the prepared MMIP for DIT reached 461.50 mg/g with lower LOD of 0.033 μg kg−1.•The MMIP can be used for specific adsorption and detection of DIT residues in food samples. In this study, molecularly imprinted polymers (MIPs) were prepared for the specific recognition of organophosphorus pesticides and a rapid, efficient and simple method was established for the detection of dimethoate (DIT) in food samples. Fe3O4 magnetic nanoparticles were synthesized by co-precipitation, and Fe3O4/ZIF-8 complexes were prepared by a modified in-situ polymerization method, and then magnetic molecularly imprinted polymers (MMIPs) were prepared and synthetic route was optimized by applying density functional theory (DFT). The morphological characterization showed that the MMIPs were coarse porous spheres with an average particle size of 50 nm. The synthesized materials are highly selective for the organophosphorus pesticide dimethoate with an adsorption capacity of 461.50 mg·g−1 and are effective resistance to matrix effects. A novel method for the determination of DIT in cabbage was developed using the prepared MMIPs in combination with HPLC. The practical results showed that the method can meet the requirements for the determination of DIT in cabbage with recoveries of 85.6–121.1 % and detection limits of 0.033 μg·kg−1.