Assessment of Efficiency of Bioactive Glass, Self-Assembling Peptide, and Ozone Remineralising Agents on Artificial Carious Lesion

• Published in: Pesquisa brasileira em odontopediatria e clínica integrada Vol. 24
• Main Authors: Alessa, Noura, Shah, Shahzad Ali, Bhardwaj, Rishibha, Ismail, Prabu Mahin Syed, Mahabob, M. Nazargi, Babaji, Prashant, Ramaiah, Vardarajula Venkata
• Format: Journal Article
• Language: English; Portuguese
• Published: Associação de Apoio à Pesquisa em Saúde Bucal 01.01.2024; Association of Support to Oral Health Research (APESB)
• Subjects: Dental Caries; Dental Enamel; DENTISTRY, ORAL SURGERY & MEDICINE; Efficiency; Ozone; Ozone; Dental Caries; Dental Enamel; Efficiency
• ISSN: 1519-0501; 1983-4632; 1983-4632
• DOI: 10.1590/pboci.2024.018

ABSTRACT Objective: To assess the efficacy of bioactive glass, self-assembling peptide, and ozone-remineralizing agents on the artificial carious lesion. Material and Methods: On the extracted 60 premolar teeth, an artificial carious lesion/demineralization was created. Later, the remineralization of demineralized teeth was done with respective remineralizing agents (Group A: Calcium sodium phosphosilicate (bioactive glass), Group B: Self-assembling peptide, Group C: Ozone remineralizing agents and Group D (Control): De ionized water. The degree of demineralization and remineralization were evaluated using the Vickers Hardness Number. Results: There was a decrease in microhardness from baseline to demineralization in all the groups, and this reduction was found to be statistically considerable. After the remineralization of demineralized samples with respective remineralizing agents, there was an increase in microhardness of 312.38, 276.67, and 254.42 in groups A, B, and C, respectively. In contrast, in Group D, there were no changes. Conclusion: Bioactive glass and self-assembling peptides had higher remineralizing capacities, which can be used to treat early carious lesions.