Role of Helicobacter pylori in Rosacea

• Published in: Bezmialem science Vol. 6; no. 1; pp. 6 - 8
• Main Authors: EMIROGLU, Nazan, CENGIZ, Fatma Pelin, GULSEL BAHALI, Anil, BIYIK OZKAYA, Dilek, KUCUK, Ozlem Su, ONSUN, Nahide
• Format: Journal Article
• Language: English
• Published: Galenos Publishing House 01.01.2018
• Subjects: Helicobacter pylori; Helicobacter pylori antibody (Hp Ab; Helicobacter pylori antigen (Hp Ag); Rosacea
• ISSN: 2148-2373; 2148-2373
• DOI: 10.14235/bs.2018.1359

Objective:Rosacea is a chronic, inflammatory skin disease. The etiology is not known exactly, and natural immunity, impaired dermal matrix, vasodilation, and fibrogenesis may play a role in the pathogenesis of rosacea. Many studies investigated the relationship between rosacea and Helicobacter pylori (HP) but the results were contradictory.Methods:Patients were retrospectively identified from those treated by the Department of Dermatology. A total of 47 rosacea patients and 27 healthy controls were included in the study. Helicobacter pylori (Hp Ag), Helicobacter pylori immunoglobulin A (Hp IgA), and Helicobacter pylori immunoglobulin G (Hp IgG) were investigated and statistically compared in groups.There was statistically no difference between the groups in terms of Hp Ag positivity (p=0.871), Hp IgA positivity (p=0.806), and Hp IgG positivity (p=0.330).Conclusions:Although we did not observe any difference between groups, we were unable to evaluate whether there is a reduction in symptoms with HP eradication. Further studies are needed to clarify the relation between HP infections with rosacea and other dermatological disorders.